4 is 473. These abilities can be taunts, slows, roots, and even knock-ups. It says impaired movement or actions, is a silence an impairment of actions? This thread is archived New comments cannot be posted and votes cannot be cast Related Topics League of Legends Real-time strategy MOBA Strategy. Yes, it counts as impairment and works with Weakness :) Wonderful-Onion-3393 • 2 yr. ; Heel-off: the heel lifts off the floor as the foot rises but the toes remain in contact with the floor. Isometric tremors – tend to occur while sustaining muscle activity without any movement. Tested this with a mate and I autoed him with first tick of e, then autoed again with the e slow but. Awe grants a total of 68. Earn a Bounty Hunter stack for champion takedowns, up to one per unique enemy champion. No slows count as impaired for something like cheap shot, a slow though is not an immobilizing effect. Deadman’s Plate is a tank item that champions like Sett and Garen often build. 89 may differ. The FRAT has three sections: fall risk status, risk factor checklist, and action plan. Since many neural structures are involved in generation of SP, and various factors, including age, drugs, and alertness, can influence pursuit eye movements, impaired pursuit generally does not have a localizing value . Ability power. Gear Affixes for Diablo 4. 1563. This bonus is increased to 15% Movement Speed for any enemy Champion that you Impair. Stacks decay when movement is impaired. H-28Q Apex Turret. For the expanded patch notes, see here. From there, click on “Mouse Settings,” and select “Additional mouse options. 5 / 1. Cooldown: 4s Activates on damage occurring after the impairment. sweating. Injection. Damaging champions with impaired movement or actions deals 10 – 45 bonus true damage (based on level). GG Desktop LoL App is capable of setting the right runes for any champion of your choice, you should check it out. bjpt. In this League of Legends gameplay video, we showcase an incredible Mordekaiser pull that left us in awe. Cheap Shot. While this form of crowd control isn’t as rare as blind, it is only possessed by three champions: Fiora, Malphite, and Nasus. PD and basal ganglia dysfunction are associated with impaired motor timing. This bonus is doubled to 15% toward enemy champions whose movement Ashe have impaired. If it says impaired movement, slows count in addition to anything that immobilizes. Additionally, Mordekaiser’s passive ability makes an excellent way to. A mobility impairment is a disability that affects movement ranging from gross motor skills, such as walking, to fine motor movement, involving manipulation of objects by hand. Damage to your thalamus can result in: Unconsciousness and even coma. H-28G Evolution Turret. Teemo's dance. Also, here's a shameless twitch plug. It is a service provider issue at that point most likely. With the description of new antibodies and new syndromes, both the clinical spectrum and our insights into disease pathophysiology and treatment expand. "Don't worry fam, quitting LoL is easy, I've done it at least 10 times. Ultimate Hunter. Usually, choreic movements rapidly evolve into a generalized chorea, although 20% of patients have unilateral or strongly asymmetrical involvement . The authors alone are responsible for the content and writing of the paper. ) and things such as silence. no - silverhyruler post. Multiple sclerosis is a chronic disease that affects the central nervous system, including the brain, spinal cord, and optic nerves. 25 seconds, based on his E’s rank. Draven doesn't need more power lategame nor does he need more damage or utility at any point of the game right now. Embodiment theory suggests that we use our own body and experiences to simulate information from other people’s bodies and faces to understand their emotions. NCQAC Advisory Your 7x. krazyken04 Newbie Posts: 5 Joined: Sun Jul 15, 2018 8:59 pm. At that point, instead of waiting for the champion to start moving after a second or two, the game itself moves the champion. This category lists champions that possess the ability to apply charm . Use the Ashe guide on ProGuides to find Win Rate, Pick Rate, Ban Rate, and Play Rate. Exact diagnosis: the patient has Zellweger Syndrome. A side-by-side comparison can be seen here. Higher movement speed will make it easier to escape ambushes, and can make a difference in many more phases of the game than you might think. Make it Rain (E) is the most enjoyable ability, causing bullets to fall. Variable manifestation of the pathology across individuals, coupled with differing mechanics and treatments, leads to a. Expresses feelings of anger, frustration, helplessness and powerlessness. While Charm and Taunt are active, the enemy is forced to move toward the source of the immobilizing effect. So effectively, your movement speed would be 0. In path 10. In general, cerebral palsy causes impaired movement associated with exaggerated reflexes, floppiness or spasticity of the limbs and trunk, unusual posture, involuntary movements and unsteady walking, or some combination thereof. Diagnoses and treatments based on movement system impairment syndromes were developed to guide physical therapy treatment. He was imprisoned at the end of the Great Darkin War, but escaped centuries later in the remade. Abilities refers to a champion's castable spells (by default , , , and ). 4 MS. #2 - Standard Build Items Standard build items for Jungle Fiddlesticks (Image via mobafire. Nocturne’s Fear duration is 1. 1111/nyas. The reason they don't is because a lot of champs with knockups have that being the only real thing going for them. Malph is more or less an ult machine in teamfights, and make it so you can get a lot of tenacity on that makes him a lot worse. If multiple slows affect a champion at the same time then the strongest is applied. Pain, tingling, numbness in your hands or feet. This can lead to increased risks of mental health challenges, such as anxiety and. Additional detrimental effects identified for them were the loss of upright standing and locomotion, freezing in movement, joint stress, pain, and changes in gait patterns. Attacks removes all Momentum. It affects percentage slows that are enemy-sourced and self-sourced (also called "self-slows" — e. the weather report or news. 29 votes, 19 comments. 8. Eyeball Collection. While upper-extremity movement in individuals with neurological disorders such as stroke and spinal cord injury (SCI) has been studied for many years, the effects of spasticity on arm movement have been poorly quantified. When exercising after an injury has healed, start back slowly, using lighter weights and less resistance. Cerebral palsy (CP) is caused by a static lesion to the brain occurring in utero or up to the first 2 years of life; it often manifests as musculoskeletal impairments and movement disorders including spasticity and contractures. Isn't it 2% each second over 3 seconds , doubled when movement impaired, so a total of 6% or 12%, or am I being stupid now? Oppression was a tier 5 Defense mastery with 1 rank. Hypoglycemia affects a person’s movement and ability to think clearly, which can cause serious accidents, especially while driving or working. 65 or 29. V12. 1 Movement speed caps 1. Rigidity. Attack windup reduced to 20% from 20. People with ataxia may show a loss of balance, slurred speech, stumbling, and unusual eye movements. A unit that is charmed is forced to move directly toward the Source (the unit that casted the Charm spell), during which they're unable to perform issued movement commands. Thalamic aphasia (jumbled words, meaningless speech). For all associated collection items, see Teemo (Collection). By Gil Wayne BSN, R. The exclusion criteria were: (1) cognitive or speech impairment affecting communication; (2) new infarcts or bleeding; (3) impaired movement of shoulder, elbow, or wrist due to trauma, soft tissue injury, fracture, frozen shoulder, joint contracture; (4) serious comorbidities such as digestive and endocrine system, or psychiatric disorders. Yep, they stack additively. Grants 2. Coma is unresponsiveness from which the patient cannot be aroused and in which the patient's eyes remain closed. Cooldown: 4 seconds. Higher movement speed will make it easier to escape ambushes, and can make a difference in many more phases of the game than you might think. 2 his R scaling was buffed for lategame. Falls Risk Assessment Tool (FRAT) is a 4-item falls-risk screening tool for sub-acute and residential care. 4 AD or 9 AP) Shield Flex 6 Armor Teemo is a champion in League of Legends. Ezreal's Arcane Shift or Shen's Shadow Dash). Neuromyotonia is a distinctive movement disorder characterised by continuous muscle fibre activity (complex repetitive discharges). Removal/Resistance: While Tenacity reduces the duration of slows, slow-resist reduces their potency. Damaging champions with impaired movement or actions deals 10 – 45 bonus true damage (based on level). Biography. The facial muscles, also called craniofacial muscles, are a group of about 20 flat skeletal muscles lying underneath the skin of the face and scalp. | Meaning, pronunciation, translations and examplesRole: Juggernaut/SupportMeleePassive: Joy at the Sight - Mobus heals when a champion gets their movement impaired around him. 3 Research Group MOVANT (Movement Antwerp), Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Science, University of Antwerp, Antwerp, Belgium. Abnormal postures of the feet and hands may occur resembling carpopedal spasm. 23 Patch Notes Champions Performance. Bug Fix: Bonus gold gained is now properly tracked in the End of Game screen. e. Unspeakable Horror Nocturne. I have played league since season 2, and I just found this. 25 / 1. In LoL's variety of psuedo rng, you start with a lower than actual crit chance, that increases every time don't crit, and decreases after successive crits. -Knockup In addition to preventing all attacks, movement, abilities, and the use of Flash and Teleport, knockups also cause. V12. A unit that is suppressed is unable to control its movement, declare attacks, cast abilities, activate items or use any summoner spell for the duration. Ataxia may cause uncoordinated or clumsy balance, speech or limb movements, and other symptoms. On modes without structures or structures are impervious,. e. Parkinsonian tremors – occurs at rest and improves with voluntary movements. 5% increased damage against units with impaired movement (airborne, slow, stun, snare, taunt, suppression). During this duration, enemies are completely incapacitated, unable to cast spells or auto-attack. Slide your other leg down, STOP if pain is experienced in your back. It’s a mechanic that is only useful when playing on high MS (80+). If movement is inhibited or impaired, an individual may be less able to participate in goal directed movement, in a safe and efficient manner. Caring Service Layout available: Impaired Physikal Activity, Alteration to Activity Ignorance, Inability at Ambulate, additionally Small Range a Motion (ROM) Are you want to view adenine video learning on how in design an care plan in skilled school, please regard to video below. 45*0. 4. ago. Eyeball Collection Collect eyeballs for champion takedowns. V5. This chapter deals with the examination of five aspects of ocular function: fixation, saccadic movements, pursuit movements,. It's also always active against lee sin and whatever champ crows is playing. Gain an adaptive bonus of 1. After you have done this, a tiny interface will pop up in front of you and. Affected units now run away from Fiddlesticks with impaired movementThere are some perks in the resolve rune that require you to "impair" enemy movement. the liver becomes abnormally large, build-up of peroxisomes, excess amount. Movement includes basic movement and mobility abilities (i. Momentum: Moving builds Momentum, granting up to 40 Move Speed at 100 stacks. This bonus is doubled to 15% toward enemy champions whose movement Ashe have impaired. Introduction. Arena differences edit Health changed to 500. If you’re predisposed to seizures, your risk of having a seizure may also increase during the. [1][2] Fine motor disability is a symptom of an underlying disease process rather than a disease in its own right. 4, and rounding makes it the same as your shown movement speed. As functional movement disorders (FMDs) can be. DOI: 10. However, what constitutes a negated word is ill-defined and varies from domain to domain and problem to problem since terms, like canceled or diverted, would not always be considered negated. Every Style grade gives her bonus movement speed. The SenpAI. Cooldown: 4s. Slurred, slow or low-volume speech (dysarthria) Visual disturbances, such as blurred or double vision and difficulty focusing your eyes. Movement speed slows do not stack, so if you get hit by a 20% and a 40% slow then you are slowed by 40%, not 48 or 60. Anything that impedes movement so any Soft CC and Hard CC. From a neuropathological perspective, cerebellar purkinje cells, responsible for modulating input from the cerebellum to the cortex, have decreased size and linear density in. Onslaught of Shadows. There is no single test or scan for Parkinson’s, but there are three telltale symptoms that help doctors make a diagnosis: Bradykinesia (slowness of movement) Tremor. Patch History. This new movement speed will be reduced by 35%. lol Registrieren Female and License. ago. 20 bonus AD, +0. First of all you can reach 100% slow resist by having phase rush (75%) and boots of swiftness (25%). Furthermore, Samira equips both a sword and gun, allowing her to deal melee and ranged auto attacks. N. Alternating movements with the arms or legs. Riot are finally addressing League’s mobility creep problem in Season 11 though, making big cuts to dashes and movement speed buffs. His W E and R do it. Causes of Flashing Lights in the Eyes. To sum it up, the Movement Prediction option is. Literally nobody (including Draven mains their selves) say Draven need more damage or utility. 4. 2 Other 3 Increasing flat movement speed. But, when applied to movement, they are. I find it strange that this item still has the damage buff against movement-impaired units. Timing abnormalities have been reported in many neurological disorders, including Parkinson's disease (PD). Very similar idea with Alistar and Rakan. com)Impaired movement perception means only slow-moving or static objects are seen. all cc except silence count towards immobilizes stun, slow, snare/root, suppression, sleep (zoe), polymorph (lulu), fear, and taunt. It’s rich, blood red, and its shiny skin gleams in the light. Samira can also damage enemies at range with her guns or with her sword in melee range; the latter dealing bonus magic damage. Since that is above 415, the first soft cap applies. Warwick gains damage reduction for 2. For example, Reina et al. TheWhiteWolves • • 5 yr. 25 seconds causing them to run away from Nocturne with impaired movement if they do not get out of (465. You're right that liandry's burn does more damage to movement impaired people, and rylai's slows people when hit with abilities which counts as them being movement impaired, so the 2 synergize well. Independent finger movements were differentially impaired in humans with lesions relatively restricted to the motor cortex or corticospinal tract. , 2017, Kramer et al. Morde is really good pick into tank teamcomps and champions that fights in melee range. When the somatosensory cortex sustains damage, this can result in sensory deficits and, due to its location, can even affect movement and. Q: Pulse - Mobus casts a pulse wave infront of him that lasts . The motor fibers through which the brain communicates with the legs travel through this vulnerable region of the brain and, therefore, movement difficulty affecting the legs is a frequent consequence of brain injury in the preterm infant. Impaired scapular movement refers to insufficient or excessive range, alteration in orientation, or inappropriate timing of scapular movement in relation to humeral motion. high level electrical activity, which results in an altered state of arousal; other effects depend on which region of cerebrum is activatedIMPAIR definition: If something impairs something such as an ability or the way something works, it damages. Both are considered 'impaired movement' for the purposes of Apporach Velocity, Liandry's and such likings. You deal true damage on. Fears and Charms are more powerful slows and take control away from the players afflicted by them. A unit that is suppressed is unable to control its movement, declare attacks, cast abilities, activate items or use any summoner spell for the duration. THC, a psychoactive compound in marijuana, can impair movement and coordination by interacting with brain areas that control movement and by stimulating the release of dopamine. To effectively treat the problem, one must look outside of the isolated area to assess the function of the entire movement. 12615. Note: Activates on damage occurring after the impairment. CH 13: Movement 186 Case 1: Movement Disorder with Fall Injury, 187 Case 2: Movement: Impaired Nerve and Sensory Function, 195 Conceptual Debriefing & Case Reflection, 204 Conceptual Quiz: Fundamentals and Advanced, 205 CH 14: Comfort 207 Case 1: Impaired Tissue Integrity and Pain, 208 Case 2: Acute Pain, 217Download. The most prevalent and well-known symptoms of Alzheimer’s disease (AD) and its precursor amnestic mild cognitive impairment (aMCI) [] are cognitive deficits, specifically memory problems. Approach Velocity. Every Style grade gives her bonus movement speed. Find Ashe builds, counters, guides, masteries, runes, skill orders, combos, pro builds, and statistics by top, jungle, mid, adc, and support in S10. 7. Note that attacks or abilities that impair the target will not trigger that bonus damage themselves, unless the target is already slowed or immobilized. Warm up, stretch, and cool down. 75 / 2 / 2. Deal bonus true damage to enemy champions with impaired movement or actions. One of the ancient darkin, Varus was a deadly killer who loved to torment his foes, driving them almost to insanity before delivering the killing arrow. 5% bonus movement speed when moving toward a movement-impaired enemy champion. Ezreal's Arcane Shift or Shen's Shadow Dash). This is a count of sub-movements representing. Avoid activity involving an injured body part. Symptoms can range from muscle weakness to vision loss. Asperger syndrome ( AS ), also known as Asperger's syndrome, formerly described a neurodevelopmental condition characterized by significant difficulties in social interaction and nonverbal communication combined with restricted and repetitive patterns of behavior and interests. Lift one knee toward your chest. Background Comprehensive treatment strategies are needed for individuals with glenohumeral joint osteoarthritis (OA), especially when they are young and active. In PD, motor-timing impairments are especially debilitating in gait. In PD, slowed movements or impaired finger-tapping performance has been associated with hypoactivation of the basal ganglia circuitry, the supplementary motor area, and premotor area. Posture and movement planning, preparation, and execution of a goal-directed reaching movement are impaired in individuals with stroke. Object Moved This document may be found herePatch V3. In this article, we’ve gathered all the Diablo 4 gear affixes and organized them by gear type and class. Teemo. This article section only contains champion skins. The contribution of hyoid and laryngeal movement deficits to penetration or aspiration in dysphagia is unclear, partly due to large variations in normal hyolaryngeal kinematics for swallowing. Case 4. 300 max damage vs. 25 / 1. A test battery consisting of six active movement control tests, based on descriptions by Sahrmann and O'Sullivan [9,10,13,19,22], and which has been published in our earlier papers [] {Luomajoki, 2008 #379} was applied. Time Warp Tonic - Your. Impaired champions in a 180° total angle towards the user's facing direction are valid targets. One point of movement speed translates to one game-distance unit traveled per second (as a frame of reference, Teemo's hat is circa 100 game-distance units in diameter). A PT can help you figure out which muscles have impaired vs. What are the odds?"-. Many involuntary muscle movements have several possible causes. If it says immobilized, slows do not count. Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. Just think what kind of champions are using this item right now: Rumble. If you are still struggling get Liandries and shiet tons of CDR. . 3000Slow resist, also Slow resistance, is a stat that reduces the strength of multiplicative (= percentage) slows. Implicit learning with impaired movement dynamics 1513 Disabil Rehabil Downloaded from informahealthcare. Basic research has only just begun to investigate forelimb function after spinal cord injury (Girgis et al. The aim is to have you still crit 50% of the time, but with no unlikely lucky or unlucky chains. What are the different types of nystagmus?. 5 seconds. Champions’ abilities and movement actions are completely nullified. Most physical damage is based on the champion's attack damage, but not all damage based on attack damage does physical damage; a small number of champion abilities. In the affected hands, the independence of the thumb was normal, and the independence of the index finger was slightly impaired, while the independence of the middle, ring, and little fingers was. ; V12. Disables are any effects/conditions that can be 'cleansed' by a stunbreak, but there are at least 2 exceptions - Taunt and Fear - they are both soft and hard CCs - can be cleansed with stunbreaks and/or condi cleanse. Momentum decays while movement is impaired. Perhaps the most common and effective way to regain mobility after stroke paralysis is to practice passive exercises. 1016/B978-0-444-64150-2. This bonus is doubled to 15% toward enemy champions whose. Treatment. ; V10. 3. Disable in the in game optins - movement prediction - it should fix the problem :) Weakness is the Domination rune choice for most supports because it is the only Domination rune that can amplify the damage of the whole team. It ability be a temporary, permanent or worsening problem and has the potential in create larger…Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level). Finally, she can extend the CC duration on movement impaired opponents by juggling. Download and install the Wooting Double Movement application. NSS, like impaired movement sequencing, seem to be a result of impaired coordination between these cortico-cerebellar areas involved in the motor system . Impairing the movement of enemy champion means a wide range of crowd controls. Nystagmus is a rapid, involuntary, shaking, “to and fro” movement of the eyes. Despite impaired audiomotor synchronization, PD patients' gait improves when they walk with an auditory metronome or with music. PASSIVE: Your attacks and damaging abilities deal 12 - 30 (based on level) bonus true damage to Stun icon impaired enemy champions. Mikael's Blessing. I think the question being asked here is whether each tick of damage from liandry's reapplies rylai's slow, which they do not and to my knowledge. 22. For example, although the. an immobilized guardian can still activate Leap of. Attacks deal magic damage equal to Momentum stacks removed. A substantial number of studies have shown that motor behavioral deficits are common in aMCI and AD as well []. Disable WASD keyboard movement bindings and lock input method as mouse in Fortnite. 18. We recommend using the table of contents jump below or Cntrl + F to help you find what you’re looking for. V13. In addition, the finding that women and girls exhibit differences in lower extremity kinematics and neuromuscular control as compared with men and boys may help explain why woman and girl athletes are at a. This is the American ICD-10-CM version of R26. Boards;Appraoch Velocity: Gain 7. Requires 16 points in. • 5 yr. Dystonia can be anatomically categorized as focal (affecting one or two parts of the body), segmental, multifocal, and. This post was co-authored by Stacey Humphries, Ph. Often, people cannot control their arms and legs, making them take wide, unsteady steps when they walk. Font of Life restores 40% of the total heal on-hit, then 15% after 0. Haste: Attacking with max Momentum grants 25% Attack Speed for 4 seconds. Champions can only be linked by one Knight's Vow at a time. Another movement symptom, postural. Physical damage is dealt by all basic attacks, and is also dealt by some abilities and item effects. Reddit community and fansite for the free-to-play third-person co-op action…Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level). To ensure smooth gameplay, the Movement Prediction option trades moment-to-moment accuracy for responsiveness in League of Legends. 75 / 2 / 2. As pointed out by others, the tether before doesn't CC anything by itself. All types of crowd control effects in League of Legends. In combination with Rylais you always do the 12% current (not max, im stupid ) hp dmg over 3 seconds. This study utilized StartReact (SR) responses elicited by loud. ; Mid-stance: the weight is aligned and balanced on this leg. Added; Tier 4 Ferocity mastery with 1 rank. The remorseless, ruthless Shauna Vayne secures her place as the best late-game champion in League of Legends. causes low muscle tone and inability to move. Handwriting that becomes progressively smaller. Several reports have indicated that force control in Parkinson's disease is impaired during both voluntary movements 96,97 and locomotion 98. These findings help explain observations of impaired voluntary movement in FND as tested on finger tapping (Criswell et al. Sightless Kombat, a blind Killer Instinct (2013) player who’s done well playing competitively online with Xbox Live, has a great video commentary on YouTube explaining how he uses the game’s audio settings to calibrate it for playing while blind. Their attack speed is also reduced by 75% of the slow. Hearing impaired tip: Sign language. Maintenance times have now been confirmed, and will begin at 03:00 AM PT for NA. Senna. 625 from 0. A doctor can perform tests or exams and make treatment, therapy, or referral recommendations. Movement speed slows do not stack, so if you get hit by a 20% and a 40% slow then you are slowed by 40%, not 48 or 60. Font of Life does not interact with Echoes of Helia's Soul Siphon. Notably, our assessment tool was able to discriminate between athletes with a history of concussion –. AD participants with a high subcortical WML load had more symptoms of parkinsonism than controls with a low lesion load, controls with a high lesion load, and. . Assessment. 584K subscribers in the Warframe community. Symptoms of constipation include bloating, abdominal discomfort, straining during bowel movements, and the sensation of incomplete evacuation. This article section only contains champion skins. "Don't worry fam, quitting LoL is easy, I've done it at least 10 times. Rhythmic auditory stimulation in Parkinson gait rehabilitation. No studies have shown whether the deficits are generally impaired or are specific to the lesioned hemisphere/paretic arm. io. Taste of Blood: Heal when you damage an enemy champion. Basic attacks expend all Momentum to deal bonus magic damage equal to the number of stacks. Our instant delivery, special warranty and 24/7 support means there is simply no better place to get your LoL smurfs. 75- 2 seconds. This impairment was most prominent for transitive (object-related. This review shows that aging and chronic conditions result in wide-ranging losses in physical. 001. Additionally, poor movement can lead to and/or perpetuate pre-existing painful conditions; a vicious cycle begins, feeding pain and deeper functional pathology, a phenomenon known as the. Adam Newell - November 19, 2023. This matters to me since this could be very beneficial or not with the mastery oppressor. A recent systematic review found that people with chronic neck pain have lower proprioceptive acuity than people without pain (Stanton et. Taste of Blood: Heal when you damage a champion. Unique Passive - Momentum: Moving builds Momentum, granting 50 bonus movement speed at 100 stacks. - Every aspect of Ashe's kit impairs the movement of her opponents (besides E), which. Mikael's Blessing. Selective motor control (SMC) is an essential element of normal human movement that enables agile, independent control of joint motion. He was the starting jungler for Legacy Genesis helping them qualify for the OPL defeating Sudden Fear 3-0. Roof movement impaired. Innovative solutions (9) (active tab) Forum topics (0) You are looking for all the solutions related to Impaired movement. It is important to stress that the distinction between movement structure and movement dynamics does not necessarily correspond to the distinction between explicit. Impaired started out as a substitute for Legacy Esports, then Chiefs Esports Club. notable increase in weight over past month- gain of 17 pounds. Pain, redness, or irritation at site where injected.